HEFT: eQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors
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چکیده
منابع مشابه
HEFT: eQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors
MOTIVATION Identification of expression Quantitative Trait Loci (eQTL), the genetic loci that contribute to heritable variation in gene expression, can be obstructed by factors that produce variation in expression profiles if these factors are unmeasured or hidden from direct analysis. METHODS We have developed a method for Hidden Expression Factor analysis (HEFT) that identifies individual a...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2013
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btt690